Editor in Chief Dr KK Aggarwal, Padma Shri Awardee                                                                                Dated:3 November,2019

FDA statement on ranitidine testing results

The FDA has released a summary of the results of testing numerous ranitidine products on the market over the past few months for N-Nitrosodimethylamine (NDMA). The levels of NDMA in ranitidine are similar to the levels you would expect to be exposed to if you ate common foods like grilled or smoked meats. Tests that simulate what happens to ranitidine after it has been exposed to acid in the stomach with a normal diet were also conducted and results of these tests indicate that NDMA is not formed through this process. Similarly, if ranitidine is exposed to a simulated small intestine environment, NDMA is not formed. “However, we still must test the drugs in the human body to fully understand if ranitidine forms NDMA”, says the FDA.

For reference, consuming up to 0.096 micrograms or 0.32 parts per million (ppm) of NDMA per day is considered reasonably safe for human ingestion based on lifetime exposure. FDA has set the acceptable daily intake limit for NDMA at 0.096 micrograms or 0.32 ppm for ranitidine. Although many manufacturers have already recalled ranitidine voluntarily, FDA will recommend recalls to manufacturers with NDMA levels above the acceptable daily intake limit… (Source: US FDA, November 1, 2019)


AQI even more than 10 is harmful to human health

I am in Tokyo for the annual meeting of the Japan Medical Association and I see people wearing anti-pollution masks. When I enquired about the AQI levels, to my surprise, they were only 60.

Remember, the air quality in Delhi-NCR has been ranging between 'severe' to 'very poor' category, especially after Diwali, with the overall air quality index (AQI) levels more than 400. In some places, it has crossed even the 500 mark. Delhi continues to be enveloped in a thick layer of smog. ....read more


Childhood cognitive skills affect future cognitive performance
(Excerpts from American Academy of Neurology): How well eight-year-olds score on a test of thinking skills may be a predictor of how they will perform on tests of thinking and memory skills when they are 70 years old, according to a study published October 30, 2019 in Neurology. Education level and socioeconomic status were also predictors of thinking and memory performance.

The study involved 502 people all born during the same week in 1946 in Great Britain who took cognitive tests when they were eight years old. Between the ages of 69 and 71, participants took thinking and memory tests again. ....read more


Sattchittaananda: The soul characteristics, (Absolute Existence –Absolute Knowledge)
Satt means ‘truth or knowingness’
Chitta means ‘consciousness-based’
Ananda means ‘bliss or inner happiness’

The soul in Vedic description is described as Sattchittaananda. People in touch with their soul speak the truth, take consciousness-based decisions and experience inner happiness. ....read more


Healthcare News Monitor

Delhi hospitals see rise in cases of respiratory, cardiac complications; kids, elderly worst hit
ET Healthworld- PTI

New Delhi: As air pollution reached alarming levels in the national capital, hospitals reported a surge in the number of patients suffering from respiratory and breathing complications, with doctors advising residents, especially children and the elderly, to stay indoors as much as possible. Pollution levels in the region entered the "severe plus" category on Friday, with the Supreme Court-mandated pollution control body EPCA declaring a public health emergency in Delhi-NCR and banning construction activity till November 5. With poor air quality prevailing in the national capital for the past three days, there has been a rise in the number of patients visiting out-patient departments (OPDs) or emergencies with respiratory or cardiac related problems. "Patients are coming with complaints of watery eyes, cough, breathing difficulty, allergy, exacerbation of asthma and chronic obstructive pulmonary diseases (COPD)," AIIMS Director Randeep Guleria said, adding that children and those above the age of 60 are the worst affected when the pollution levels are high. Besides affecting lungs, high levels of pollutants in the atmosphere cause inflammation in blood vessels and may lead to hardening of arteries which can act as a trigger for stroke or heart attack in persons, already at risk of the disease, Guleria explained.

India’s life expectancy rises to 68.7 years, says National Health Profile 2019
The Hindu-IANS

Life expectancy in India has increased from 49.7 years in 1970-75 to 68.7 years in 2012-16, as per the National Health Profile 2019 released on Wednesday. For the same period, the life expectancy for females is 70.2 years and 67.4 years for males. For comparison, in last year’s survey, the life expectancy had increased from 49.7 years in 1970-75 to 68.3 years in 2011-15. For the same period, the life expectancy for females is 70 years and 66.9 years for males. On the non-communicable diseases (NCD), the survey notes that out of 6.51 crore patients who attended NCD clinics, 4.75% people are diagnosed with diabetes, 6.19% are diagnosed with hypertension, 0.3% are diagnosed with cardiovascular diseases, 0.10% are diagnosed with stroke and 0.26% are diagnosed with common cancers. According to the survey, the highest population density of 11,320 people per square kilometre was reported by the National Capital Territory of Delhi (NCT) whereas Arunachal Pradesh reported the lowest population density of 17. On demographics, the survey found the high incidence of the young and economically active population. The survey notes that 27% of the total estimated population of 2016 were below the age of 14 years and majority (64.7%) of the population were in the age group of 15-59 years i.e. economically active, and 8.5% population were in the age group of 60-85 plus years.

Rise in prevalence of non-communicable diseases in India: Govt report
Moneycontrol

There is an accelerated rise in the prevalence of chronic non-communicable (NCD) ailments such as diabetes and hypertension and they dominate communicable diseases in the total disease burden of the country, a government report stated. In a recent report of India Council of Medical Research (ICMR) titled India: Health of the Nation's States: The India State-Level Disease Burden Initiative (2017), it is observed that the disease burden due to communicable, maternal, neonatal, and nutritional diseases, as measured using disability-adjusted life years (DALYs), dropped from 61 per cent to 33 per cent between 1990 and 2016. In the same period, disease burden from non-communicable diseases increased from 30 per cent to 55 per cent. According to the National Health Profile 2019, 6.51 crore patients were screened at NCD clinics as part of the National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS) from January 1 to December 31, 2018. Of these, 4.75 per cent of patients were diagnosed with diabetes, 6.19 per cent with hypertension, 0.3 per cent with cardiovascular diseases, 0.10 per cent with stroke and 0.26 per cent were diagnosed with common cancers.

Gujarat stands first in India when it comes to cancer diagnoses
ET Healthworld - Ahmedabad Mirror

According to the National Health Profile 2019, Gujarat has the highest number of people who were diagnosed with different types of cancers during medical check-up at Non-Communicable Diseases (NCD) clinics in 2018. The data, sourced from the National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS) — between January 1, 2018 and December 31, 2018 — shows Gujarat diagnosed 72,169 patients with oral, cervical or breast cancer, which is the highest number in India. However, it must also be taken into account that Gujarat is among only 11 states where more than 10 lakh patients were checked during 2018. Among these 11 states, number of persons checked at NCD clinics in Andhra Pradesh were 13.82 lakh, Haryana (12.92 lakh), Gujarat (39.97 lakh), Karnataka (23.75 lakh), Kerala (47.58 lakh), Maharashtra (58.83 lakh), Rajasthan (89.54 lakh), Tamil Nadu (2.39 crore), Telangana (28.50 lakh), Uttar Pradesh (30.43 lakh) and West Bengal (14.58 lakh).