Editor in Chief Dr KK Aggarwal, Padma Shri Awardee                                                                               Dated:16 May,2020

Why daily virus numbers mean little in post-lockdown stakes

Wondering whether it’s safe to emerge from lockdown? Watching the daily coronavirus case trackers won’t help much. A better indication might come from the length of the lines outside the doctor’s office.
To strike the right balance between restarting the economy and guarding against new waves of the pandemic, countries must focus on more than daily infection numbers and death tolls, according to scientists....read more


CMAAO-IMA Coronavirus Facts and Myth Buster 96 - Vaccines

(With inputs from Dr N K Ganguly, Dr Rajan Sharma, Dr RV Asokan)
841: Coronavirus vaccines
General:1.Coronaviruses: Virus Spike protein, Envelope, Membrane, RNA, Nucleic
2.Difficulties: Virus behaves like HIV, causes immune inflammation, causes cytokine storm, causes thrombo-inflammatory reactions, brings down immunity and has latency ....read more


World COVID Meter 14th May: Living with COVID 1.0: End Social pandemic of fear before the medical pandemic

212 Countries affected, Crosses 4.42 M, Nearly 90K cases and 5K deaths per day
Minimum Likely Deaths 301947, Deaths to Cross 300,000 today and total number 5 M by 21st May
Wuhan re-testing 11M people in 10 days as 6 new cases surface; South Korea 100 new cases linked to night club; Singapore R0>1, Germany R0 < 1; 3 new cases Hong Kong ....read more


The Spiritual Meaning of Lord Shiva

Most of us worship Lord Shiva without understanding the deeper meaning behind him. In Hindu mythology, Shiva is one of the three forms of God (Brahma, Vishnu and Mahesh).
The Parmatama or spirit or GOD can be equated to a mixture of three forces representing Generator, (Creator or Brahma); Organizer; (Maintainer or Vishnu); Destroyer (Winding up or Mahesh or Shiva). The same three forces are also present inside our body to perform any work,....read more


Video of The day

Emotional Personal Protective Equipment


Medbytes

       


Healthcare News Monitor
Antiviral drugs see demand surge in India, but segment declines 5.5%
Business Standard- Sohini Das

With the pandemic raging across the world, the demand for antiviral drugs — especially those used for treating influenza or HIV — have shot up as they are being tested as potential cures for Covid-19. Data from market research firm AIOCD-AWACS shows that sales of oseltamivir (common brand Tamiflu), used against the influenza virus and also for swine flu, went up by 35.8 per cent in April on a year-on-year (YoY) basis. Similarly, drugs like tenofovir and its combinations (anti-HIV drugs) have seen significant traction. Domestic sales of the much touted combination of lopinavir and ritonavir grew over 50 per cent in April. On the whole, the antiviral segment registered a drop of 5.5 per cent on a YoY basis. On the export front, too, antivirals have remained in demand. Speaking to Business Standard, Uday Bhaskar, the director general of Pharmaceutical Export Promotion Council (Pharmexcil) said demand for antivirals was high as most countries were experimenting with treatment protocol for Covid-19. Vamsi Krishna Bandi, managing director of the Hetero Group, said they have been supplying the combination of lopinavir and ritonavir to European countries. Demand for hydroxychloroquine and paracetamol remained high during March and April, said Bhaskar.

Pune-based NovaLead gets DCGI nod for clinical trials of 'promising' coronavirus drug
Business Today – P B Jayakumar

Pune-based drug discovery company NovaLead Pharma has received final phase clinical trial permission from the Indian regulator Drug Controller General of India (DCGI) for an undisclosed repurposed drug, which it claims to have shown better efficacy than any existing treatments currently being used in COVID-19 treatment across the world. Codenamed NLP21, NovaLead said the drug is in human use for several years for its original use without any side effects. A comparable study conducted by reputed laboratories in South Korea and the United States has shown better viral inhibition ability than Remdesivir, Fevipiravir, Hydroxychloroquine and Lopinavir/Ritonavir. These drugs are currently being tested for treating COVID-19 worldwide, but are yet to conclusively prove efficacy. "It shows promising ability in the treatment as it prevents virus from binding to the human cells and reduce the viral load and also clears damaged human cells to allow regeneration of healthier cells. These are essential to address COVID-19 infection effectively," said Supreet Deshpande, CEO of NovaLead. Further, the drug has shown ability to prevent multiplication of the disease causing germs. According to him, the trial permission was given in four days. Normally in India, an approved drug does not require elaborate data and clinical trials for getting approved for use in other diseases. NovaLead claims its trial drug will be the second drug for treating COVID-19 to enter Phase 3 trials in India.

Rajkot: Pregnant woman slaps female doctor
The Times of India- TNN

A female gynaecologist was allegedly abused and slapped by two women including a pregnant woman and her motherin a governmentrun Padmakunvarba Hospital in Gundavadi area of the city late on Wednesday night. In her complaint lodged with the police, Dr Arva Soni, 25, identified the pregnant woman as Amri, her mother Roshan and husband Zahid. Dr said that the trio came to the hospital at around 11:30pm, after Amri started having labour pains. However, the woman reportedly got agitated after Dr Soni asked them to remove their footwear outside the labour room. Amid a brief argument, Amri allegedly slapped her twice, followed by her mother who too hit the doctor. Even Zahid hurled expletives at Dr Soni before the trio left from there.

Iraqi doctor''s fight with virus lays bare a battered system
Outlook India

Dr. Marwa al-Khafaji''s homecoming after 20 days in a hospital isolation ward was met by spite. Someone had barricaded her family home''s gate with a concrete block. The message from the neighbors was clear: She had survived coronavirus, but the stigma surrounding the disease would be a more pernicious fight. The young physician was catapulted into the front lines of Iraq''s battle with the virus in early March. The Associated Press followed her tale from inside a squalid quarantine room to her return to the streets of her childhood, where she found piercing glares had displaced greetings. Her struggles mirror those of Iraq''s battered health system, laid bare by the pandemic: Hospitals without supplies, medical staff intimidated by an unknown disease, and widespread stigma associated with infection. Fear of stigma — driven by religious beliefs, customs and a deep mistrust of the health system — has been a main driver of the pandemic in Iraq, doctors say, as people hide their illness and avoid seeking help. At least 115 people have died among more than 3,030 confirmed coronavirus cases across Iraq, according to Health Ministry statistics. The daily rate of cases jumped after curfew hours were shortened for the holy month of Ramadan, from 29 on April 22 to 119 on Wednesday. Officials fear a flare-up would be catastrophic. Iraqi officials described the ministry''s response as adequate and said Iraq was spared the exponential rise in cases seen in neighboring Iran and Turkey. Ministry spokesman Saif al-Badr blamed the spread on people who had symptoms or came from an affected country and "didn''t disclose these facts due to arrogance.” But Khafaji''s story, as well as interviews with half a dozen doctors and nurses, reveal a haphazard response with no comprehensive strategy from a hobbled government that until recently had only caretaker status. “Inside quarantine, the future felt uncertain,” Khafaji said. “Outside it''s no different.” In mid-March, Khafaji, 39, grew alarmed when her elderly mother, Dhikra Saoud, showed signs of respiratory distress. The virus had just started to hit Iraq and had yet to leave its mark on the city of Karbala where she lives.