Editor in Chief Dr KK Aggarwal, Padma Shri Awardee
Dated: 19th May, 2019
Is there something like plant-based Vigara drugs?
The introduction of PDE5 inhibitors (Viagra-like drugs) is associated with a proliferation of herbal products purporting to enhance male sexual function.
Many of these ‘natural’ products contain concealed substances, which are structurally modified analogs of the PDE5 inhibitors.
Unlike the parent pharmaceutical, no formal studies have been performed to assure the safety and efficacy of these analogs.
Their producers appear to trust that such analogs have clinical effects (and toxicity) similar to those of the corresponding parent compounds. This assumption is not always correct.
Methylenedioxymethamphetamine (Ecstasy), an analog of amphetamine, is associated with a higher frequency of serotonin syndrome and symptomatic hyponatremia.
N-nitrosofenfluramine, an unregistered analog of fenfluramine, causes fatal hepatic failure not observed with the parent drug.
The adverse effects of drug analogs are highly unpredictable and the consumption of such products is dangerous.
New drugs must undergo extensive testing before being marketed for human use
Weather variations can affect and alter body functions: Heart Care Foundation of India
Recent statistics indicate that between 2030 and 2050, weather extremes are expected to cause around 250,000 additional annual deaths from malnutrition, malaria, diarrhea and heat stress. Extreme heat can make a person feel hot and sweaty and further cause dehydration and heat stroke particularly in people at risk. This includes young children, people over 65 years of age, and those with pre-existing medical conditions like diabetes and heart disease.
The need of the hour is to raise awareness on importance of drinking adequate water and staying out of the heat as much as possible. This can help in preventing dehydration and other heat-related problems.
The early summer season or grishma ritu is hot and dry, while the later part of summer, when rains are on the horizon, is hot and moist. Rains are not usual in early summer in North India. However, this year, early summer has been marked by an unusually increased frequency of dust and thunderstorms, and rains. In Vedas, this is termed vikruti (vitiation) of ritu (season), when the weather forgets its dharma and behaves abnormally. When this happens, all body circadian rhythms also behave abnormally, and body functions are exaggerated. In such weather conditions, wind-sensitive individuals with no evidence of target organ damage can have accelerated hypertension. They are also sensitive to changes in atmospheric pressure.”
Vitiation of vata (movement) leads to high blood pressure, arrhythmia; pitta (metabolism) increases metabolism and more acidity, while vitiated kapha (structure) may disrupt sugar profile. Any change in environment affects the functions of the body, something that is well-known in Vedic sciences. For instance, the current weather profile in Delhi can lead to the development of accelerated hypertension.
The significance of a ‘medical vrata’ needs to be underlined for everyone during summer.
A simpler version of ‘vrata’ can be: not eating carbohydrates at all once in a week and replacing them with fruits and vegetables.
Some summer tips from Heart Care Foundation of India
Current Temperature Status and Warning for next 24 hours
Heat Wave and Temperature Observed Yesterday (Past 24 hours from 0830 hrs IST of 18 May to 0830 hrs IST of 19 May, 2019)
Yesterday, Heat Wave Conditions observed at isolated pockets over Vidarbha and Madhya Maharashtra. (Annexure 1 & 2).
Maximum Temperature more than 40.0°C were recorded at most places over East Madhya Pradesh, Vidarbha, Marathwada, Rayalaseema, Chhattisgarh and Telangana; at many places over East Uttar Pradesh, Madhya Maharashtra, Coastal Andhra Pradesh, North Interior Karnataka and Rayalaseema; at a few places over Bihar, Jharkhand, Odisha and Tamilnadu & Puducherry and at isolated places over Saurashtra & Kutch, Gangetic West Bengal & Sikkim.
Maximum temperature departures as on 19-05-2019: Maximum temperatures were appreciably
above normal (3.1°C to 5.0°C) at most places over Rayalaseema and North Interior Karnataka; at
many places over Bihar, Gangetic West Bengal, Kerala and Madhya Maharashtra; at a few places
over Chhattisgarh, Sub-Himalayan West Bengal & Sikkim and South Interior Karnataka; above
normal (1.6°C to 3.0°C) at most places over Jharkhand; at many places over Odisha, Telangana,
Marathwada and Tamil Nadu & Puducherry; at a few places over Nagaland, Manipur, Mizoram &
Tripura, Vidarbha, Lakshadweep and Coastal Karnataka and at isolated places over Coastal
Andhra Pradesh. They were markedly below normal (- 5.1°C or less) at a few places over
Uttarakhand and Haryana, Chandigarh & Delhi; appreciably below normal (-3.1°C to -5.0°C) at
most places over Rajasthan; at many places over West Uttar Pradesh; at a few places over Jammu
& Kashmir, Himachal Pradesh, East Uttar Pradesh and Punjab; at isolated places over Madhya
Pradesh and Assam & Meghalaya; below normal (-1.6°C to -3.0°C) at many places over
Arunachal Pradesh; at a few places over Andaman & Nicobar Islands and Gujarat Region; at
isolated Saurashtra & Kutch and near normal over rest of the country.
Heat Wave Warnings for Next 24 hours (From 0830 hrs IST of 19 May to 0830 hrs IST of 20 May 2019):->
Heat Wave Conditions in some parts very likely over Vidarbha and in isolated pockets over Chhattisgarh, Bihar, Jharkhand, Gangetic West Bengal, Odisha, Madhya Maharashtra, Marathwada, North Interior Karnataka, Telangana and Tamilnadu & Puducherry. (For significance of colour code and criteria for Heat Wave, kindly refer to Annexure-3 at end of this document)
Woman contracted hepatitis C after hysterectomy
After a wait of 10 years, the South Mumbai Consumer Disputes Redressal Forum recently directed the doctors and the Bombay Hospital & Medical Research Centre to grant a compensation of Rs 5 lakh to a woman who contracted a life-threatening virus after undergoing a hysterectomy.
In July 2007, 53 year old Ms MD had a hysterectomy performed at the hospital and in September the same year, she developed Hepatitis 'C' (itching, fever and yellow eyes). She sought a compensation of Rs 19.71 lakh from the respondents.
The forum held that Ms. Diwakar suffered from Hepatitis C, and has to take regular drugs and medicines to control it, for which she has to bear the medical expenses. She is suffering from heavy financial loss as well as mental torture and her reputation in society is also badly affected.....read more
Is it right to stop research on any subject?
Recently, the Ministry of Health & Family Welfare, Government of India issued a communication on the subject of electronic nicotine delivery systems and like devices to a total of 35 stakeholders, including all the Councils, ICMR, medical colleges, National Academy of Medical Sciences (NAMS), National Board of Examination (NBE), among others, among others.
The circular dated 5th May 2019 said, "Since the subject matter is sub-judice and pending before various high courts. It is requested not to publish any statement/ research paper/ document/ article/ report/ study etc as well as not to organise any consultation/ workshop etc on ENDS and the likely devices that enable nicotine delivery without prior consultation with tobacco control division MOH and FW....read more