Editor in Chief Dr KK Aggarwal, Padma Shri Awardee                                                                               Dated:21 December,2019

Merck says Ebola vaccine to be available at lowest access price for poor nations

The vaccine, Ervebo, was approved by the U.S. Food and Drug Administration on Thursday, a month after Europe gave its nod to the vaccine, a move that has been hailed by the World Health Organization.

Merck & Co said on Friday it expects to make licensed doses of its recently approved Ebola vaccine available in the third quarter of 2020 and price the single-dose injection at the lowest possible access price for poor and middle-income countries.

The vaccine, Ervebo, was approved by the U.S. Food and Drug Administration on Thursday, a month after Europe gave its nod to the vaccine, a move that has been hailed by the World Health Organization. ....read more

Five most important trials in 2019 for CMAAO Countries

ISCHEMIA Trial:Chronic coronary artery disease is not a time bomb in the chest but a condition that should be treated with reassurance, lifestyle changes, and medical therapy.

DAPA-HF trial: Dapagliflozin, a SGLT2 inhibitor reduces CV death, worsening heart failure, and overall death when used on top of optimal medical therapy in patients with heart failure due to a reduced ejection fraction. ....read more

The lips of truth shall be recognized forever; a lying tongue is but for a moment

This sutra from Bible has a very deep significance in day to day life. The truth is everlasting and always ends up in internal happiness and self realization and in the long run always gives you happiness and an all-win situation. On the contrary, a lying tongue will only give you a momentary pleasure but you will end up in some difficulty later in life. ....read more

In 2020 I would like the new healthy policy to



Healthcare News Monitor


The year is ending on a sour note for Indian pharmaceutical companies, with the Nifty Pharma index down about 10% so far. In comparison, the Nifty 50 index has risen about 10%. Unfortunately, the pharmaceutical firms may not be out of the woods in 2020. Heightened risks to the sector are likely because of an increase in the number of US FDA (food and drug administration) inspections. The domestic market could also be roiled by trade-margin caps and additions to the National List of Essential Medicines (NLEM), which is being seen as a huge overhang. US FDA inspections increased considerably in 2019 and led to Indian drug makers receiving about 23 warning letters. Indian companies account for about one official action-indicated (OAI) letter for every six inspections, which is worrisome. The global average, by contrast, is one OAI for every 12 inspections. In 2019, “we saw strict FDA action. To my knowledge in the past few years, we have not seen so many warning letters given to Indian companies in a single year", said Anshuman Gupta, analyst at Investec Capital Services (India) Pvt. Ltd. In fact, most pharma stocks that got observation letters, OAI letters, or warning letters went into a tailspin. As the US FDA inspects about 400 manufacturing plants in India every two years, risks of adverse observations remain high.

The New Indian Express

Major corporate hospitals have threatened to withdraw services under the Central Group Health Scheme and the Ex-Servicemen Health Scheme, saying that the Union government owes over Rs 700 crore to them. In a press conference on Thursday, representatives of hospitals and private healthcare professionals said hospitals were on a verge of collapse. “The Indian Healthcare industry is passing through a crisis. Thousands of crores are due to be paid by CGHS/ECHS to private hospitals. The outstanding are pending for past several months,” said a joint statement by the Association of Healthcare Providers of India and Indian Medical Association. Max Healthcare, Fortis Healthcare, Medanta, Narayana Health and HCG group of hospitals are among such affected private healthcare facilities. Repeated attempts by hospitals and associations have not yielded any response, they rued. “Non-payment of legitimate dues by the government is taking a toll on day-to-day functioning of the hospitals. Hospitals are unable to pay salaries to the employees. Many hospitals have begun to cut down the operations by closing certain wards and beds.” Hospitals are constrained to lay off the employees, they said. “If the situation is allowed to persist, it is feared that lakhs of hospital employees may lose jobs. The hospitals having been pushed to the brink of unsustainability, will be constrained to suspend cashless services for the beneficiaries of CGHS/ECHS.” Reimbursement rates for medical procedures under CGHS were not revised since 2014, said the Associations. The Associations warned that while the PM had stressed on the need for opening of new hospitals in Tier-II and III cities, the current scenario will adversely affect effectiveness of Ayushman Bharat scheme. “Considering that 70 per cent of OPD and 60 per cent of IPD patients are being taken care of by private healthcare providers, the likely disruption of health services due to financial crunch is going to impact the national healthcare scenario more so in tertiary care where private sector provides more than 85 per cent of such services,” they said.

DownToEarth- Sunderarajan Padmanabhan

Women who been infected by chickenpox may transmit the DNA of the disease-causing virus to their babies during pregnancy, stimulating their immunity against the infection and protecting them, a study found. This mother-to-child transfer of viral DNA may be responsible for long-lasting protection against chickenpox infection seen during childhood, researchers from National Institute of Immunology and St Stephens Hospital, Delhi, said. Their study was published in journal Viral Immunology. The new finding takes the understanding on how babies are protected against infections such as chickenpox to a new level. Currently, it is understood that mothers provide babies protection against a variety of common infections by transferring readymade antibodies to them. The protection lasts for 12-15 months; if a baby catches an infection during this period, it gets ill in a mild form and develops its own long-lasting immunity for that disease. The new study led by Jacob Puliyel from St Stephens Hospital showed that it was, however, different in the case of chickenpox. Scientists found that mothers developed subclinical viremia and the viral DNA was transferred to their babies. The study was done in 350 mothers and their newborn babies. “The babies of mothers, who had chickenpox earlier in their life, develop a long-lasting active immunity with the transfer of chickenpox DNA from mothers, instead of the short-term passive protection provided by the transfer of readymade antibodies. It is likely that the antibodies are developed actively in the foetus,” researchers said. “Several studies have already shown that chickenpox can get reactivated due to stress following surgeries and space travel. But, subclinical reactivation of chickenpox, induced by the stress of pregnancy, is being reported for the first time,” they added.


On Thursday, the anti-Citizenship Amendment Act protests in Mangaluru turned violent. Two persons were shot dead by the police and a third with bullet injuries is recovering in the hospital following a surgery. The administration imposed curfew in several areas of the district and mobile internet services were suspended for 48 hours. By Thursday night, CCTV footage showing the police barging into the Highland hospital in Falnir and chasing people with batons began to circulate on social media. There were claims that the police had used teargas shells inside the intensive care unit of the hospital. To understand the timeline of events that led to the violence in the area, Scroll.in spoke to two eyewitnesses. One was outside the hospital during a face-off between protesters and the police. The other, a senior hospital official, was inside the premises when the police force in riots gear barged in. According to the hospital official, while the police did not use teargas inside the intensive care unit, the shell was dropped in the lobby located about 30 metres from the hospital rooms and the ICU.