Editor in Chief Dr KK Aggarwal, Padma Shri Awardee                                                                               Dated:25 May,2020

Scientists studying Covid ‘mindset’ to defeat virus

Hyderabad: Joining the world race to understand the ‘mindset’ of Covid-19, which is wreaking havoc on human lives, Indian scientists have unravelled the genetic secrets of the novel coronavirus circulating in the country. They have found that the isolates obtained from Covid-19 patients in India have a high entropy for changes or mutations in two sets of polyproteins (ORF1a and ORF1b) as compared to the novel-coronaviral strains circulating in other parts of the world. ....read more


CMAAO Coronavirus Facts and Myth Buster 104 Mantra, Alphabets and Speech

(With inputs from Dr Monica Vasudev, Ashok Chakradhar and Preti Prajapati)
893: Speech May Spread COVID-19Yes, Normal human speech is capable of emitting droplets that can carry the novel coronavirus (SARS-CoV-2). The droplets may linger in the air for up to 14 minutes, thus reinforcing the importance of masking.
894: Talking, shouting, talking loudly, singing, coughing and sneezing all can transmit the infection. [Valentyn Stadnytskyi, from the National Institute of Diabetes and Digestive and Kidney Diseases, and colleagues, May 13 in PNAS.]....read more


World Covid Meter 23rd May: Living with COVID 1.0: End Fear Pandemic

212 Countries affected, Nearly 100 K cases and 5 K deaths per day, Minimum Likely Deaths 346610, Total cases 5.3 M
Cases: 1M: April 2, 2 M April 15, 3 M: April 27, 4 M May 8; 5 M 20 May,Ground Zero: Wuhan - in live animal market or cafeteria for animal pathogens: 10th January.,Total cases are based on RT PCR; 67% sensitivity
Doubling time India 14 days, USA 27 days, UK 27 days, Spain 40 days, Russia 13 days, Italy 46 days, Brazil 11 days, France 41 days, Germany 44 days, Turkey 30 days, Malaysia 42 days, Singapore 20 days, China 67 days, HK 50 days ....read more


Self-esteem in Mythology

For spirituality, one needs to control two things, first, lust and then the ego. Among, Kama, Krodha, Lobha, Moha and Ahankara, ego and lust both are slow poisons and do not allow one to be spiritually healthy. There are many examples of how to control ego in mythology. Fundamentally, it is said that one should learn to kill ego of oneself and never hurt the ego of others....read more


Video of The day
Can X ray chest decide the severity of COVID infection


Medbytes

       


Healthcare News Monitor
Covid-19 crisis prompts India to look for global partners in health care
Business Standard- Sohini Das

As India shifts its focus to the pharmaceutical and medical devices industries amid the Covid-19 pandemic, it is actively reaching out to several countries, including Japan, seeking to attract investments in manufacturing and joint venture projects, according to officials and industry executives. India sees an investment potential ofRs 70,000 crore in the medical devices industry alone over the next five years. The government is targeting 1,200 technical collaborations between Japanese companies and Indian investors for over 42,000 crore, 200 joint ventures with overseas investors forRs 14,000 crore, and another 14,000-crore investment from about 50 multinational companies. This was discussed during a webinar organised by the Indian Embassy in Tokyo, along with the Department of Pharmaceuticals, and it had over 150 participants from both countries. P D Vaghela, secretary, Department of Pharmaceuticals , who was also present in the webinar, said Japanese companies were interested in investing in the API (active pharmaceutical ingredient) space, and could also explore joint ventures in the medical devices segment. Speaking to Business Standard, Sudarshan Jain, secretary-general of the Indian Pharmaceutical Alliance (IPA), said companies like Eisai Pharmaceuticals had been operating in the country since the early 2000s and their experience had been good. “India can be a low-cost manufacturing base for Japan. We have skilled manpower and at lower costs. India is one of the largest suppliers of generic medicines to the US; it can do the same for Japan,” Jain said. He said partnerships or investments could be in different kinds of projects. One is where a Japanese company sets up a manufacturing base here for exporting to other countries, or it can export to Japan. Secondly, they can also invest in Indian companies that make drugs. Moreover, with India’s renewed focus on growing its API production, there are a lot of investment opportunities for Japanese majors. Eisai, for example, makes APIs. “The Indian government is now offering production-linked incentives for large API production units and this can be an area of collaboration,” Jain said.

Bureaucratic indifference delays clinical trial of drug for Covid-19
The Pioneer- Kumar Chellappan

Even as the country is struggling hard to contain the coronavirus pandemic which is spreading all over with vigor by the hour, indifference of bureaucrats towards the medicine developed to minimise and regulate the contagious disease is causing irreparable damage to the soul of India. While scientists specialising in modern medicine are groping in the dark in search of a vaccine to fight the coronavirus pandemic, an Ayurvedic drug and protocol developed by a team of eminent Ayurvedic physicians in collaboration with modern medicine specialists is given a raw deal by the bureaucrats of the Ministry of Ayush. The details of the drug and treatment protocol was submitted to the Ayush Ministry on April 15 this year. Messages to Shripad Yesso Naik, Union Minister of State (Independent Charge) did not evoke any response. Dr Rajesh Kotecha, eminent Ayurvedic physician , who is also the secretary to the Ayush Ministry chose to ignore the messages sent to him requesting for details about the clinical trials. The team of doctors that developed the ayurvedic drug prepared from the age old Indian system of knowledge was led by Dr PR Krishnakumar, South India’s leading Ayurvedic scholar and included a who’s who of medical researchers. Dr Rama Jayasundar of All India Institute of Medical sciences, New Delhi, a physicist turned ayurvedic researcher, Dr CV Krishnaswamy, Tamil Nadu’s leading physician, Prof B M Hegde, described as the country’s medical warrior are some of the members of the team that developed the drug and protocol. Dr Krishnakumar has been honoured by the nation with Padma Sree while Prof Hegde is a Padma Bhushan with hundreds of publications in national and international journals. It was Prof Hegde who declared in his pathbreaking research work “What Doctors Don’t Get To Study in Medical School” that the drug for coronavirus and influenza would come from India.

Being the first contact, resident doctors face high risk
The Hindu- Afshan Yasmeen

When an 82-year-old patient was wheeled into the Chigateri District Hospital in Davangere in a critical condition on a hot afternoon earlier this month, his first point of contact was a postgraduate resident doctor on duty at the ICU. The 27-year-old final year anesthesiology student, who was on duty that day, intubated the patient who had gone into respiratory distress and started treating him. The patient was a suspected COVID-19 case and was admitted in the suspect zone of the ICU. Though the patient later tested negative, there is no denying the risk factor in such cases. Resident doctors such as the anesthesiology student are often the first point of contact in many such cases. “We are under risk while intubating as the patient can fight against the insertion by gagging or other reflexes. Initially, we were doing it only wearing masks but now we have been provided face shields,” the doctor told The Hindu. “I was posted in the ICU that has both suspected and positive zones. I am now under quarantine after a week’s duty,” said the doctor. A resident doctor from Bangalore Medical College and Research Institute who finished his COVID-19 ward duty at the Emergency and Trauma Care Centre has a wound on his nose at the point where the N95 mask sticks. “As resident doctors we are used to working in long shifts spanning 36 to 48 hours normally. But, it is suffocating to wear the personal protection equipment (PPE) continuously for six hours. This gets stretched to seven hours if we include the time spent on donning and doffing and bathing after duty. By the time we finish our shift, we are drenched in sweat. As we cannot drink water or use the washroom during our shift, most of us are experiencing dehydration, hypoxia due to decreased supply of oxygen, headache, dizziness, and fatigue due to carbon dioxide retention as well as skin rashes,” said the doctor.

Doctors strike a note of caution as lockdown eases
The Hindu

Members of the Indian Medical Association(IMA) of Chittoor district chapter and A.P. Government Doctors’ Association on Sunday said that there was need for a stricter facemask norm and awareness among people to combat COVID-19. The chapter president, P. Ravi Raju, deplored that with relaxations in the lockdown, people had thrown the precautions to wind, and warned that one must continue wearing a mask for at least one year to protect self and others from the virus. “A face mask prevents the spread of the virus by 90%. A majority of the cases at the isolation centres in the district are found to be asymptomatic. Unknowingly, infected persons may pass it on to others, endangering the lives of many,” Dr. Ravi Raju said. At a meeting with the ASHA workers and paramedical staff at the Primary Health Center at Narayanavanam, Dr. Ravi Raju instructed them to educate people about the facemask norm as a preventive measure. He said the COVID task force should rope in medical staff of the Social Preventive Medicine(SPM) department of the various medical colleges in the State for containment measures.